We are seeking an energetic and highly motivated R&D Specialist for Regeneron’s Immunoscreening group in Therapeutic Proteins department with a focus on neuroscience and skeletal diseases. We are involved in reagent characterization, screening and identification of potential therapeutic antibodies and contribute to early discovery stage in-vitro characterization of the lead molecules.
In this role, a typical day might include performing the following:
•Develop robust assays to characterize existing and new reagents for neuroscience, skeletal and carbohydrate targets.
•Execute assays according to established protocols as a part of antibody high throughput screenings.
•Perform assays under BSL-2 conditions for protocols involving infectious agents.
•Optimize immunoassays to assess antibody therapeutics functional properties with referencing protocols and using robotic systems.
•Aid in optimization of assays for in-vitro quantitative characterization of the lead antibodies.
•Learn and utilize ELISA, MSD, ALPHALISA, Fluoresence and Fluoresence Polarization for studying antigen-antibody interactions.
•Develop peptide micro array based epitope mapping.
•Compile and analyze data utilizing Excel, Prism and other graphing software.
•Evaluate and implement new instrumentation and methods to characterize protein interactions.
•Inform manager and the project team of experimental results, prepare written and oral presentations to the screening team and interdepartmental project team.
•Keep accurate records of experimental procedures and results.
This job might be for you if:
•You enjoy working productively in a fast-paced collaborative environment.
•You have an eye for detail and pride yourself on the quality of your work.
•With your sleeves rolled up, you work on current problems while thinking of future solutions.
•You have excellent interpersonal and communication skills.
To be considered for the role, you must have a minimum of two years of experience with a Master’s degree or four years’ experience with a Bachelor’s degree with knowledge of immunology and protein biology and hands-on bench research/development experience. Strong background in in-vitro protein characterization, such as ligand/receptor binding characterization and quantitative potency determination, protein structure-function relationship in the field of biochemistry or immunology. Skilled in aseptic techniques and human and mouse cell culturing. Familiarity with working principles of Fluorescence, ELISA and MSD. High throughput screening experience and familiarity with liquid handlers.Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.